Antibodies under a microscope

Ab00140-23.0

125-2H

Description

Recombinant monoclonal antibody to IL-18. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 125-2H. This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Target

IL-18

Target Alias Names

Iboctadekin, Interleukin 18 (Interferon-gamma-inducing factor), IGIF, IL1F4, IL-1g

Isotype/Mimetic

IgG

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

recombinantly reformatted hybridoma (from pre-2020 immunisation)

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression