Antibodies under a microscope

Ab00126-10.139

10F381 (rituximab)

Description

Recombinant monoclonal antibody to CD20. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody 10F381 (rituximab). This format contains the STR complete Fc Silencing mutations from mAbsolve.

Target

CD20

Target Alias Names

Leu16, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35 Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20

Isotype/Mimetic

IgG1-STR

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression