Description
Enables several functions, including ATPase binding activity, calmodulin binding activity, and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade, negative regulation of angiotensin-activated signaling pathway, and peptidyl-serine dephosphorylation. Located in cytoplasm, cytoplasmic side of plasma membrane, and dendritic spine. Part of calcineurin complex. Implicated in developmental and epileptic encephalopathy 91. Biomarker of cholangiocarcinoma, focal segmental glomerulosclerosis, and schizophrenia. [provided by Alliance of Genome Resources, Jul 2025]