Description
The antibody is a Human IgG1, kappa targets General S1P/Sphingosine-1-phosphate
Target
S1P/Sphingosine-1-phosphate
Target Alias Names
S1P, Sphingosine-1-phosphateHuman Anti-S1P Recombinant Antibod SONEPCIZUMAB pleiotropic signaling lipid sphingosine-1-phosphate (S1P)A humanized monoclonal antibody directed against sphingosine 1-phosphate (S1P) with potential antiangiogenic and antineoplastic activities. Upon administration, sonepcizumab binds S1P, which may result in the inhibition of tumor angiogenesis. S1P is the extracellular ligand for the G protein-coupled lysophospholipid receptor EDG-1 (endothelial differentiation gene-1).
Isotypes/Mimetics
IgG1, kappa
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
Unknown
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression