Description
The antibody is a Humanized Humanized IgG4-kappa, anti-human TIGIT fused at the C-terminusof the heavy chain, via a (G4S)4 peptide linker, to a fragment of the mature extracellular domain of human TGF-beta receptor type-2. targets Human TIGIT & TGFBR2
Target
TIGIT & TGFBR2
Target Alias Names
VSTM3, TIGIT, V-set and transmembrane domain-containing protein 3, VSIG9, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains, TGFR-2, TbetaR-II, TGF-beta type II receptor, TGFBR2, TGF-beta receptor type-2, TGF-beta receptor type II, Transforming growth factor-beta receptor type II
Isotypes/Mimetics
Humanized IgG4-kappa, anti-human TIGIT fused at the C-terminusof the heavy chain, via a (G4S)4 peptide linker, to a fragment of the mature extracellular domain of human TGF-beta receptor type-2.
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
Unknown
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression