Description
Phospho-Btk (Tyr223) (D1D2Z) Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of Btk protein only when phosphorylated at Tyr223. The antibody detects a 26 kDa protein of unknown identity that is not sensitive to treatment with anti-IgM or Ibrutinib. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr223 of human Btk protein.
Target
BTK (Tyr223) phosphate
Target Alias Name
Btk
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression