Description
Recombinant monoclonal antibody to H3K27me3. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 2E12LI. This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
H3K27me3
Target Alias Names
Trimethylated Histone H3 Lys27, trimethyl-Histone H3 (Lys27), histone H3, H3K27, Trimethylated histone H3, Histone H3 trimethylated at Lysine 27, nucleosome, H3K27ME3, post translational modification, histone post-translational modification, 2E12 mutant M86L/M158I, 2E12
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
active immunisation (post 2020) during discovery
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery, post-2020, In vitro recombinant expression