Description
Recombinant monoclonal antibody to Nerve growth factor. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 4D4 (Fulranumab; CNTO7309). This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG2 format, for improved compatibility with existing reagents, assays and techniques.
Target
Nerve growth factor
Target Alias Names
NGF, NGFB, Beta-nerve growth factor, Beta-NGF, AMG-403, JNJ-42160443, CNTO-7309
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression