Description
Recombinant monoclonal antibody to MDA-5. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from The phage display library 76F-MDA5-R2P1-G5. This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
Target
MDA-5
Target Alias Names
RLR-2, Helicard, CADM-140 autoantigen, Helicase with 2 CARD domains, Murabutide down-regulated protein, RIG-I-like receptor 2, RNA helicase-DEAD box protein 116, Interferon-induced with helicase C domain protein 1, Melanoma differentiation-associated protein 5, Clinically amyopathic dermatomyositis autoantigen 140 kDa, Interferon-induced helicase C domain-containing protein 1
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression