Description
Recombinant monoclonal antibody to CD49B. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the synthetic antibody GBR500 (Vatelizumab, TMC-2206). This reformatted human antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
Target
CD49B
Target Alias Names
ITGA2, Integrin α2β1, Integrin alpha-2/beta-1, Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, BHA2.1, SAR339658
Isotype/Mimetic
IgG4-S228P
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression