Description
Recombinant monoclonal antibody to TNFR1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the alpaca peripheral lymphocyte Nb70. This chimeric human antibody was made using the variable domain sequences of the original Alpaca VHH format, for improved compatibility with existing reagents, assays and techniques.
Target
TNFR1
Target Alias Names
TNFRI, Tumor necrosis factor RI, Tumor necrosis factor R1, Tumor necrosis factor receptor type 1-associated death domain protein, TNFR1-associated death domain protein, TNFRSF1A-associated via death domain, Nb 14, Nanobody 14
Isotype/Mimetic
IgG1-Fc Fusion
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression