Description
Recombinant monoclonal antibody to DR4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the human B cell clone HGS-ETR1 (Mapatumumab; TRM-1).
Target
DR4
Target Alias Names
CD261, TR4, TNFRSF10A, APO2, TRAILR1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, T1014A04
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression