Description
Recombinant monoclonal antibody to TROP2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the synthetic antibody hRS7 (Sacituzumab). This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
TROP2
Target Alias Names
EGP-1, TACSTD2, GA733-1, M1S1, TROP-2, Tumor-associated calcium signal transducer 2, epithelial glycoprotein-1 antigen, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1, IMMU-132, RS7, RS7-3G11
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression