Antibodies under a microscope

Ab03387-23.0

Anti-GM2 [DMF10.167.4], Rabbit IgG, kappa

Description

Recombinant monoclonal antibody to GM2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma DMF10.167.4. This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG format for improved compatibility with existing reagents assays and techniques.

Target

GM2

Target Alias Names

ganglioside GM2, Tay–Sachs ganglioside, β-D-GalNAc-(1→4)-[α-Neu5Ac-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1)-N-octadecanoylsphingosine

Isotype/Mimetic

IgG

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

recombinantly reformatted hybridoma (from pre-2020 immunisation)

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression