Description
Recombinant monoclonal antibody to GM2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma DMF10.167.4. This chimeric mouse antibody was made using the variable domain sequences of the original Hamster IgG format for improved compatibility with existing reagents assays and techniques.
Target
GM2
Target Alias Names
ganglioside GM2, Tay–Sachs ganglioside, β-D-GalNAc-(1→4)-[α-Neu5Ac-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1)-N-octadecanoylsphingosine
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression