Description
Recombinant monoclonal antibody to EGFRvIII. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 806. This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
Target
EGFRvIII
Target Alias Names
de2–7 EGFR, EGF receptor, delta2–7 epidermal growth factor receptor, Epidermal Growth Factor Receptor variant III
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression