Description
Recombinant monoclonal antibody to CTLA4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1B8. This chimeric mouse antibody was made using the variable domain sequences of the original Hamster, Armenian IgG format, for improved compatibility with existing reagents, assays and techniques.
Target
CTLA4
Target Alias Names
Cytotoxic T-lymphocyte protein 4, Ctla4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, UC10-4FIO
Isotype/Mimetic
IgG2a
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression