Description
Recombinant monoclonal antibody to Neuregulin-HBD (Heparin binding domain, Type I/II). Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma N120A/9.1. This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Targets
Neuregulin-HBD (Heparin binding domain, Type I/II)
Target Alias Names
N120A/9.1R, Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-deriv
Isotype/Mimetic
IgG2b
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression