Description
Recombinant monoclonal antibody to CD11b. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma M1/70. This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Target
CD11b
Target Alias Names
Mac-1 alpha, CD11 antigen-like family member B, CD11B (p170), cell surface glycoprotein MAC-1 alpha subunit, cell surface glycoprotein MAC-1 subunit alpha, complement component receptor 3 alpha-a, complement receptor type 3, CR-3 alpha chain, integrin alpha-M, leukocyte adhesion receptor MO1, macrophage antigen alpha
Isotype/Mimetic
IgG2a
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression