Description
Recombinant monoclonal antibody to TIGIT. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 4D4. This chimeric mouse antibody was made using the variable domain sequences of the original Hamster format, for improved compatibility with existing reagents, assays and techniques.
Target
TIGIT
Target Alias Names
VSIG9, T Cell Immunoreceptor With Ig And ITIM Domains, V-Set And Immunoglobulin Domain Containing Protein 9, V-Set And Transmembrane Domain Containing Protein 3, VSTM3, T Cell Immunoreceptor With Ig And ITIM Domains, Washington University Cell Adhesion Molecule, WUCAM
Isotype/Mimetic
IgG2a
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression