Antibodies under a microscope

Ab00958-13.12

Anti-CD257 (BAFF) [Tabalumab], Human IgG4-S228P, kappa

Description

Recombinant monoclonal antibody to CD257 (BAFF). Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma Tabalumab. This reformatted human antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Target

CD257 (BAFF)

Target Alias Names

TNFSF20, B-cell activating factor, Tumor Necrosis Factor Superfamily Member 13b, BAFF, Tumor Necrosis Factor (Ligand) Superfamily, Member 13b, Dendritic Cell-Derived TNF-Like Molecule, TALL-1, TALL1, ZTNF4, BLYS, Tumor Necrosis Factor (Ligand) Superfamily, Member 20, Tumor Necrosis Factor Ligand Superfamily Member 13B, TNF- And APOL-Related Leukocyte Expressed Ligand 1, TNF And ApoL-Related Leukocyte Expressed Ligand 1, Tumor Necrosis Factor-Like Protein ZTNF4, TNF Homolog That Activates Apoptosis, Tumor Necrosis Factor Ligand 7A, ApoL Related Ligand TALL-1, B-Lymphocyte Stimulator, B Lymphocyte Stimulator, CD257 Antigen, Delta4 BAFF, Delta BAFF, TNLG7A, THANK, DTL, LY 2127399, LY2127399

Isotype/Mimetic

IgG4-S228P

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression