Description
Recombinant monoclonal antibody to DR4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma mAY4. This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Chicken scFv format, for improved compatibility with existing reagents, assays and techniques.
Target
DR4
Target Alias Names
CD261, Death receptor 4, Tumor necrosis factor receptor superfamily member 10A, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAILR1, TRAIL-R1, TRAILR 1, TNFRSF10A, APO2
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression