Description
Recombinant monoclonal antibody to CD146. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody IR94. This full-length, chimeric human antibody was made using the variable domain sequences of the original ScFv format, for improved compatibility with existing reagents, assays and techniques.
Target
CD146
Target Alias Names
MUC18, melanoma cell adhesion molecule, MCAM, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen
Isotype/Mimetic
IgG4-S228P
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression