Antibodies under a microscope

Ab00813-1.32

Anti-PD-1 [RMP1-14], Mouse IgG1-D265A, Fc Silenced, kappa

Description

Recombinant monoclonal antibody to PD-1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma RMP1-14. This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Target

PD-1

Target Alias Names

CD279, PD1, PDCD1, RMPI-14, RMP1/14, Programmed Death Receptor 1, Programmed Death 1

Isotype/Mimetic

IgG1-D265A

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

recombinantly reformatted hybridoma (from pre-2020 immunisation)

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression