Antibodies under a microscope

Ab00743-10.3

Anti-CD40 [A54 scFv], Human IgG1, Fc Silent™, lambda

Description

Recombinant monoclonal antibody to CD40. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody A54 scFv. This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.

Target

CD40

Target Alias Names

TNFRSF5, A54, Tumor necrosis factor receptor superfamily member 5, B cell surface antigen CD40, B-cell cell surface antigen CD40, B-cell surface antigen CD40, B cell surface antigen CD40, antigen CD40, CD40 antigen, Bp50, Bp-50, CD40L receptor CDw40

Isotype/Mimetic

IgG1

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression