Description
The described is a fully human monoclonal antibody 4B6 against human sonic hedgehog homolog (Shh). 4B6 is useful in the treatment studies of diseases associated with the activity and/or overproduction of Shh and as diagnostics.
Target
SHH
Target Alias Names
Sonic Hedgehog, Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains, ShhNC, Sonic Hedgehog (Drosophila) Homolog, Sonic Hedgehog Homolog (Drosophila), Sonic Hedgehog Homolog, Sonic Hedgehog Protein, MCOPCB5
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression