Description
Provided is an antibody against human Fas, employing the antibody VH and/or VL domain of the antibody molecule termed F45D9, which may be in IgG4 format. The antibody can be used in inhibiting Fas-mediated apoptosis and in various diseases and disorders.
Target
FAS
Target Alias Names
Fas Cell Surface Death Receptor, Tumor Necrosis Factor Receptor Superfamily, Member 6, Fas (TNF Receptor Superfamily, Member 6), Apoptosis-Mediating Surface Antigen FAS, TNF Receptor Superfamily Member 6, FASLG Receptor, CD95 Antigen, TNFRSF6, APT1, FAS1, Mutant Tumor Necrosis Receptor Superfamily Member 6
Isotype/Mimetic
Human IgG4
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression