Description
Provided are antibodies that are capable of specifically binding PCSK9. Western blot with anti-LDLR antibody show that all five anti-PCSK9 antibodies (508.20.84, 508.20.33b, 508.20.04b, 508.20.28b, 508.20.06) prevented LDLR downregulation in mouse liver.
Target
PCSK9
Target Alias Names
Proprotein Convertase Subtilisin/Kexin Type 9, Subtilisin/Kexin-Like Protease PC9, NARC-1, NARC1, PC9, Convertase Subtilisin/Kexin Type 9 Preproprotein, Hypercholesterolemia, Autosomal Dominant 3, Neural Apoptosis Regulated Convertase 1, Neural Apoptosis-Regulated Convertase 1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression