Description
This product is a recombinant humanized antibody that recognizes factor Bb. The humanzied monoclonal antibody selectively block the binding of factor Bb to the PC3bB complex without inhibiting classical pathway activation. These antibodies do not inhibit the interaction of C3b to factor B.
Target
CFB
Target Alias Names
BF, FB, BFD, GBG, CFAB, CFBD, PBF2, AHUS4, FBI12, H2-Bf, ARMD14
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression