Description
Provided is a neutralizing monoclonal antibody chC15.2 to Macrophage Stimulating Protein (MSP). chC15.2 blocks binding of MSP to its receptor RON. The chC15.2 is produced by cloning of the light and heavy chain variable regions of the C15.2 mAb, and construction and expression as a chimeric antibody.
Target
MST1
Target Alias Names
Macrophage Stimulating 1, Macrophage-Stimulating Protein, D3F15S2, DNF15S2, HGFL, MSP, Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like)
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression