Description
Recombinant Human Antibody (OX117) is capable of binding to SIRPG, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SIRPG mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-SIRPG mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
SIRPG
Target Alias Names
SIRPG, signal-regulatory protein gamma, CD172g, SIRPB2, SIRP-B2, bA77C3.1, SIRPgamma, SIRP-gamma, SIRP beta 2, SIRP-beta-2, CD172g antigen, signal-regulatory protein beta 2, signal-regulatory protein beta-2, CD172 antigen-like family member B
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression