Description
The antibody is a human antibody that exhibits specificity for CD37. The CD37 antibody, specifically A2 and B2, can also be utilized in various other forms, such as dispersions, suspensions, or liposomes. It can be incorporated into tablets, capsules, powders, sprays, transdermal or intradermal patches, creams with or without permeation enhancing devices, wafers, nasal, buccal, or pulmonary formulations. Additionally, it can be produced by implanted cells or, after gene therapy, by the individual's own cells. When administered as a single agent, the mAb A2 significantly inhibits the growth of lymphomas, specifically Ramos lymphomas.
Target
CD37
Target Alias Names
CD37 Molecule, Tetraspanin-26, CD37 Antigen, Tspan-26, TSPAN26, Cell Differentiation Antigen 37, Leukocyte Surface Antigen CD37, Leukocyte Antigen CD37, GP52-40
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression