Description
Recombinant Human Antibody (CNTO1959) is capable of binding to IL-23, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IL-23 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IL-23 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
IL23A
Target Alias Names
IL23A, interleukin 23, alpha subunit p19, P19, SGRF, IL-23, IL-23A, IL23P19, interleukin-23 subunit alpha, IL-23-A, IL-23p19, IL-23 subunit alpha, interleukin 23 p19 subunit, interleukin-23 subunit p19, JKA3 induced upon T-cell activation, interleukin-six, G-CSF related factor
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression