Description
Recombinant Human Antibody (Fab6785) is capable of binding to IL-17A, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IL-17A mAb and CH1 region of human IgG1 and a light chain (LC) encoding VL from anti-IL-17A mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
IL17A
Target Alias Names
IL17A, interleukin 17A, IL17, CTLA8, IL-17, IL-17A, interleukin-17A, CTLA-8, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression