Description
Recombinant Human Antibody (DX-2647) is capable of binding to IGF-II, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IGF-II mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IGF-II mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
IGF2
Target Alias Names
IGF2, insulin-like growth factor 2, IGF-II, PP9974, C11orf43, insulin-like growth factor II, insulin-like growth factor type 2, insulin-like growth factor 2 (somatomedin A)
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression