Description
Recombinant Human Antibody (F5) is capable of binding to Gankyrin, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Gankyrin mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Gankyrin mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
PSMD10
Target Alias Names
PSMD10, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10, p28, p28(GANK), dJ889N15.2, 26S proteasome non-ATPase regulatory subunit 10, gankyrin, ankyrin repeat protein, 26S proteasome regulatory subunit p28, hepatocellular carcinoma-associated protein p28-II
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression