Description
Recombinant Human Antibody (2B.1.3) is capable of binding to FGFR3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-FGFR3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-FGFR3 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
FGFR3
Target Alias Names
FGFR3, fibroblast growth factor receptor 3, ACH, CEK2, JTK4, CD333, HSFGFR3EX, FGFR-3, tyrosine kinase JTK4, hydroxyaryl-protein kinase, fibroblast growth factor receptor 3 variant 4
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression