Description
Recombinant Human Antibody (4A5) is capable of binding to Emmprin, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Emmprin mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Emmprin mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Target
BSG
Target Alias Names
BSG, basigin (Ok blood group), M6, OK, 5F7, TCSF, CD147, EMMPRIN, basigin, CD147 antigen, OK blood group antigen, collagenase stimulatory factor, leukocyte activation antigen M6, extracellular matrix metalloproteinase inducer, tumor cell-derived collagenase stimulatory factor
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression