Description
This product is a Human antibody that recognizes Human SIRPA. 119 is specific for human and cynomolgus monkey SIRPα. Clone 119 potently antagonizes the SIRPα/CD47 interaction.
Target
SIRPA
Target Alias Names
BIT, MFR, P84, SIRP, MYD-1, SHPS1, CD172A, PTPNS1, tyrosine-protein phosphatase non-receptor type substrate 1, CD172 antigen-like family member A, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, inhibitory receptor SHPS-1, macrophage fusion receptor, myd-1 antigen, tyrosine phosphatase SHP substrate 1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression