Description
This product is a Human antibody that recognizes Human F11. 1213790 binds to a region adjacent to the factor XIa active site. 1213790 has an allosteric mechanism of antibody-mediated factor XIa inhibition. 1213970 is specific for factor XIa and has demonstrated anticoagulant effects.
Target
F11
Target Alias Names
FXI, PTA, coagulation factor XI, coagualtion factor XI, plasma thromboplastin antecedent, FXIa, activated FXI, activated F11
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression