Description
This product is a recombinant human antibody that recognizes LRP1, also known as IGFBP-3R. The antibody is an IGFBP-3R agonist mAb. It suppresses TNF-α-activated inflammatory NF-κ B signaling in human colon cells (HT-29).
Target
LRP1
Target Alias Names
APR, KPA, LRP, A2MR, CD91, APOER, LRP1A, TGFBR5, IGFBP3R, IGFBP-3R, IGFBP3R1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression