Description
Provided herein are Notch4 monoclonal antibodies capable of inhibiting Notch4 activity. The antibody can be used in treating or preventing recurrence of cancer, and in inhibiting or killing cancer stem cells (CSCs).
Target
NOTCH4
Target Alias Names
Notch 4, INT3, Neurogenic Locus Notch Homolog Protein 4, Notch (Drosophila) Homolog 4, Notch Homolog 4 (Drosophila), Notch Homolog 4, HNotch4
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression