Description
This recombinant human antibody recognizes human and monkey LAG3. The antibody had a limited effect on LAG3-MHCII-binding. This antibody was found to bind one or more epitopes at segments from aa 23-30, 40-66, 88-105, 123-137 and 148-152 (Uniprot ID: P18627). It binds to human LAG3 as measured by flow cytometry.
Target
LAG3
Target Alias Name
CD223
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression