Description
This product is a recombinant human antibody that recognizes HAVCR2. It exhibited binding to Kasumi-3 cells and to activated human CD8+ T cells by flow cytometric analysis. It can effectively block the binding of human or cynomolgus TIM-3 to phosphatidylserine-expressing cells.
Target
HAVCR2
Target Alias Names
Hepatitis A Virus Cellular Receptor 2, T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3, T-Cell Immunoglobulin Mucin Family Member 3, T-Cell Immunoglobulin Mucin Receptor 3, T-Cell Membrane Protein 3, HAVcr-2, TIMD-3, Tim-3
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression