Description
HPAB-M0466-YC exhibited similar binding affinity to human CD3 as murine anti-CD3 on human T cells (Jurkat). Additionally, HPAB-M0466-YC displayed strong binding to cynomolgus T cells (HSC-F). The binding of HPAB-M0466-YC to Jurkat cells (which express human CD3+) resulted in an IC50 value of 5.9 nM, while its binding to HSC-F cells (also expressing human CD3+) yielded an IC50 value of 3.8 nM.
Target
Cluster of differentiation 3
Target Alias Name
Cluster of differentiation 3
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression