Description
Provided is a human-mouse chimeric monoclonal antibody for a human von willebrand factor A3 region. The human-mouse chimeric monoclonal antibody can inhibit both combination of vWF and collagen and accumulation of thrombocyte, is good in antithrombus effect and is unlikely to have anti-mouse immunoreaction in human bodies, and moreover the probability of clinical bleeding risk can be greatly reduced.
Target
VWF
Target Alias Names
Von Willebrand Factor, F8VWF, Coagulation Factor VIII VWF, VWD, VWF
Isotype/Mimetic
Chimeric (mouse/human) IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression