Description
Provided is a novel PSMA binding antibody termed 10B3. The PSMA antibody 10B3 does not cross-compete with the state of the art PMSA binding antibody J591 and has a reduced induction of antigen shift compared to J591 and a unique reactivity with squamous cell carcinoma (SCC) cells of different origin.
Target
FOLH1
Target Alias Names
Folate Hydrolase 1, N-Acetylated-Alpha-Linked Acidic Dipeptidase I, Pteroylpoly-Gamma-Glutamate Carboxypeptidase, Folylpoly-Gamma-Glutamate Carboxypeptidase, Cell Growth-Inhibiting Gene 27 Protein, Membrane Glutamate Carboxypeptidase, Glutamate Carboxypeptidase II, Glutamate Carboxypeptidase 2, Glutamate Carboxylase II, EC 3.4.17.21, NAALADase I, NAALAD1, GCPII
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression