Description
This product is a recombinant antibody that recognizes CD40. The monoclonal antibody 21.4.1 reacts with the epitope of CD40. 21.4.1 has direct anti-tumor activity against CD40(+) tumors. This anti-tumor activity for antibody 21.4.1 was enhanced when immune cells were present.
Target
CD40
Target Alias Names
CD40 Molecule, CD40 Molecule, TNF Receptor Superfamily Member 5, CD40L Receptor, TNFRSF5, CDW40, Bp50, Tumor Necrosis Factor Receptor Superfamily, Member 5
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression