Description
This human monoclonal antibody recognizing human LINGO1 (leucine rich repeat and Ig domain containing 1) can be used as an antagonist of endogenous LINGO-I function. It can promote differentiation of human oligodendrocyte precursor cells (OPC), and promote remyelination in lysolecithin-treated brains.
Target
LINGO1
Target Alias Names
LERN1, MRT64, LRRN6A, UNQ201
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression