Description
To obtain the mouse monoclonal antibody against human CD20, the mice are given booster injections every 3-4 weeks with the murine cell lines, MG87 and/or NS/0 cells, transfected with a plasmid encoding for human CD20. Then the antibody is converted to fully human IgG.
Target
MS4A1
Target Alias Names
Membrane Spanning 4-Domains A1, Membrane-Spanning 4-Domains, Subfamily A, Member 1, Leukocyte Surface Antigen Leu-16, CD20 Antigen, CD20, Bp35, Membrane-Spanning 4-Domains Subfamily A Member 1, B-Lymphocyte Cell-Surface Antigen B1, B-Lymphocyte Surface Antigen B1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression